Technical Specifications

Specification	Details
Product Name	AOD-9604
Chemical Name	AOD-9604 / Modified hGH Fragment
Strength	5 mg
Molecular Formula	C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight	~1,815.1 g/mol
CAS Number	221231-10-3
Sequence	Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Sequence Code	YLRIVQCRSVEGSCGF
Sequence Length	16 amino acids
Modification	Intramolecular disulfide bond
Purity	≥98%
Form	Lyophilized Peptide
Classification	Synthetic hGH Fragment Analog
Intended Use	Laboratory Research Only

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Product Overview

AOD-9604 is a synthetic 16-amino-acid peptide derived from the C-terminal region of human growth hormone (hGH). It incorporates an N-terminal tyrosine and contains two cysteine residues that form an intramolecular disulfide bond, creating a constrained peptide structure.

AOD-9604 has been investigated in laboratory and clinical research primarily in relation to lipid metabolism, adipose-tissue biology, and metabolic signaling. Its development history includes investigation as a potential anti-obesity compound, although it has not been established as an approved therapeutic treatment.

The compound should be distinguished from unmodified hGH fragment 176–191, as AOD-9604 has a distinct sequence and chemical structure.

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Mechanism of Action

Experimental research has investigated AOD-9604 in relation to several biological areas:

Lipid Metabolism Research

AOD-9604 has been investigated in experimental models examining pathways involved in lipid metabolism and adipose-tissue biology.

Lipolysis Research

Laboratory studies have explored the peptide’s potential influence on mechanisms associated with the breakdown of stored lipids.

Lipogenesis Research

Experimental models have also examined AOD-9604 in relation to processes involved in lipid storage and synthesis.

Growth Hormone Fragment Research

AOD-9604 provides a research model for studying the biological activity of a specific region of the human growth hormone molecule without using the complete hormone.

Peptide Structure Research

Its intramolecular disulfide bond provides an opportunity to investigate how structural constraints influence peptide conformation and biological behavior.

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Research Applications

AOD-9604 may be investigated in laboratory settings involving:

• Lipid metabolism research
• Adipose-tissue biology
• Lipolysis research
• Lipogenesis studies
• Metabolic signaling research
• Growth-hormone fragment studies
• Peptide structure-activity research
• Disulfide-bonded peptide research
• Cellular signaling research
• Synthetic peptide research

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Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Storage around −20°C is commonly specified for lyophilized AOD-9604; follow the batch-specific CoA or supplier documentation for definitive conditions.
• Minimize unnecessary temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Protect the material from moisture and prolonged exposure to light.

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Product Features

✓ Research Grade Quality

✓ 5mg Lyophilized Peptide

✓ ≥98% Purity

✓ 16-Amino-Acid Synthetic Peptide

✓ Modified hGH Fragment

✓ Intramolecular Disulfide Bond

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

AOD-9604 is an experimental research compound. Research findings should not be interpreted as evidence of established clinical efficacy or safety for human use.

AOD-9604 has been investigated in clinical development, including research related to obesity, but it has not been established as an approved treatment for obesity or other medical conditions.

The exact purity, identity, molecular characterization, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is AOD-9604?

AOD-9604 is a synthetic 16-amino-acid peptide derived from the C-terminal region of human growth hormone and modified with an N-terminal tyrosine and an intramolecular disulfide bond.

What is the sequence of AOD-9604?

The commonly reported sequence is:

Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

or, in single-letter notation:

YLRIVQCRSVEGSCGF.

How many amino acids does AOD-9604 contain?

AOD-9604 is a 16-amino-acid peptide.

What is the molecular weight of AOD-9604?

The molecular weight is approximately 1,815.1 g/mol.

What is AOD-9604 researched for?

AOD-9604 has been investigated in research involving lipid metabolism, adipose-tissue biology, lipolysis, lipogenesis, metabolic signaling, and peptide structure-activity relationships.

Is AOD-9604 the same as hGH fragment 176–191?

They are related but should not be treated as identical compounds. AOD-9604 has a distinct chemical structure and sequence from the unmodified hGH fragment.

What form does AOD-9604 5mg come in?

AOD-9604 5mg is supplied as a lyophilized (freeze-dried) synthetic peptide intended for laboratory research.

What is the purity of AOD-9604?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Is AOD-9604 intended for human use?

No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should AOD-9604 be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.