Technical Specifications

Specification	Details
Product Name	PEG-MGF
Strength	10 mg
Chemical Name	Pegylated Mechano Growth Factor
Synonyms	PEG-MGF, Pegylated MGF, Pegylated Mechano Growth Factor
Parent Peptide	Mechano Growth Factor (MGF)
Peptide Core	IGF-1Ec MGF E-Domain
Peptide Core Molecular Weight	~2,867 Da
Sequence	YQPPSTNKNTKSQRRKGSTFEEHK
Sequence Length	24 amino acids
Modification	Covalent Polyethylene Glycol (PEG) Conjugation
Purity	≥98%
Form	Lyophilized Peptide
Classification	PEGylated Research Peptide
Intended Use	Laboratory Research Only

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Product Overview

PEG-MGF, or Pegylated Mechano Growth Factor, is a modified research peptide consisting of the MGF E-domain peptide conjugated to a polyethylene glycol (PEG) polymer.

The underlying MGF peptide corresponds to the C-terminal E-domain associated with the IGF-1Ec splice variant. PEGylation changes the peptide’s physicochemical characteristics and is investigated as a strategy for modifying peptide stability and degradation behavior.

The commonly reported MGF peptide core contains 24 amino acids with the sequence YQPPSTNKNTKSQRRKGSTFEEHK and a molecular weight of approximately 2.87 kDa. The molecular weight of the complete PEG-MGF molecule depends on the size and structure of the attached PEG chain.

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Mechanism of Action

Experimental research has investigated PEG-MGF in relation to several areas:

MGF-Related Signaling

The MGF peptide is associated with research into IGF-1 splice-variant biology and signaling pathways involved in cellular growth and tissue responses.

Muscle Biology Research

MGF-related peptides have been investigated in experimental models involving skeletal-muscle biology, cellular adaptation, and regenerative processes.

Peptide Stability Research

PEG conjugation provides a research model for investigating how polymer attachment can alter peptide stability, molecular size, and susceptibility to degradation.

Cellular Signaling Research

PEG-MGF may be investigated in experimental systems examining growth-factor-related signaling and peptide-cell interactions.

Structure-Activity Research

The compound provides researchers with a modified peptide framework for studying how PEGylation influences the characteristics and behavior of peptide molecules.

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Research Applications

PEG-MGF may be investigated in laboratory settings involving:

• Growth-factor signaling research
• Skeletal-muscle biology
• Cellular growth research
• Muscle regeneration models
• Peptide stability studies
• PEGylation research
• IGF-related signaling research
• Peptide-protein interaction studies
• Structure-activity research
• Synthetic peptide chemistry

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Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Follow the batch-specific Certificate of Analysis for exact storage requirements.
• Minimize unnecessary exposure to temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Any preparation for laboratory experiments should follow appropriate validated laboratory procedures.

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Product Features

✓ Research Grade Quality

✓ 10mg Lyophilized Peptide

✓ ≥98% Purity

✓ PEGylated Peptide

✓ 24-Amino-Acid MGF Core

✓ Modified for Peptide Stability Research

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

PEG-MGF is an experimental research compound. Its safety, efficacy, pharmacokinetics, and potential therapeutic applications have not been established for human use.

Because PEG-MGF is a conjugate consisting of a peptide and a PEG polymer, the molecular characteristics of the complete molecule depend on the specific PEG chain, linker, and attachment configuration. The applicable Certificate of Analysis (CoA) should therefore be used as the definitive source for batch-specific specifications.

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is PEG-MGF?

PEG-MGF is a PEGylated form of Mechano Growth Factor (MGF), consisting of an MGF-derived peptide core conjugated to a polyethylene glycol polymer.

What is the strength of this product?

This product contains 10 mg of PEG-MGF.

What is the molecular weight of PEG-MGF?

The unmodified MGF peptide core is approximately 2,867 Da. The total molecular weight of PEG-MGF is higher and varies according to the PEG chain used in the conjugate.

What is the sequence of the MGF peptide core?

The commonly reported 24-amino-acid sequence is:

YQPPSTNKNTKSQRRKGSTFEEHK

What does PEGylated mean?

PEGylation refers to the covalent attachment of a polyethylene glycol polymer to a peptide or protein. In research, this modification is investigated for its effects on molecular size, stability, and degradation characteristics.

What is PEG-MGF researched for?

PEG-MGF may be investigated in growth-factor signaling, muscle biology, cellular signaling, peptide stability, PEGylation, and structure-activity research.

Is PEG-MGF the same as MGF?

No. MGF refers to the peptide itself, while PEG-MGF is a modified form in which the MGF peptide is conjugated to a PEG polymer.

Is PEG-MGF intended for human use?

No. This product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should PEG-MGF be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always consult the batch-specific Certificate of Analysis for exact storage requirements.