Technical Specifications

Specification	Details
Product Name	SLU-PP-332
Chemical Name	(E)-4-Hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide
Synonyms	ERR Pan-Agonist 332, SR9861
Molecular Formula	C₁₈H₁₄N₂O₂
Molecular Weight	290.32 g/mol
CAS Number	303760-60-3
Purity	≥98% HPLC
Form	Research Compound / Powder
Classification	Synthetic Pan-ERR Agonist
Target	ERRα / ERRβ / ERRγ
Intended Use	Laboratory Research Only

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Product Overview

SLU-PP-332 is a synthetic small-molecule compound developed as an agonist of the estrogen-related receptor (ERR) family, including ERRα, ERRβ, and ERRγ.

Unlike peptide-based research compounds, SLU-PP-332 is a defined small molecule and does not have an amino-acid sequence.

Research has identified SLU-PP-332 as a useful chemical probe for investigating ERR-mediated metabolic signaling, mitochondrial function, skeletal-muscle biology, and exercise-responsive cellular pathways. Studies have demonstrated activity across the ERR family, with particularly strong activity toward ERRα.

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Mechanism of Action

Research has investigated SLU-PP-332 in relation to several biological mechanisms:

ERR Activation

SLU-PP-332 acts as a synthetic agonist of the estrogen-related receptor family, activating ERRα, ERRβ, and ERRγ. ERRα appears to be its most strongly activated subtype.

Mitochondrial Function Research

Experimental studies have investigated SLU-PP-332 in relation to mitochondrial respiration and cellular energy metabolism. Research in skeletal-muscle cells has reported increased mitochondrial respiration following exposure to the compound.

Metabolic Signaling

SLU-PP-332 has been investigated in experimental models examining metabolic pathways, including fatty-acid oxidation and energy expenditure.

Exercise-Responsive Signaling

Research has identified SLU-PP-332 as an exercise-mimetic research compound, with experimental studies examining ERR-dependent transcriptional programs associated with aerobic exercise.

Skeletal-Muscle Research

Experimental research has examined SLU-PP-332 in skeletal-muscle models, including studies of oxidative muscle fibers, mitochondrial activity, and exercise-related signaling.

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Research Applications

SLU-PP-332 may be investigated in laboratory settings involving:

• Estrogen-related receptor research
• ERRα / ERRβ / ERRγ signaling
• Mitochondrial biology
• Cellular respiration research
• Skeletal-muscle research
• Exercise-responsive signaling
• Metabolic pathway research
• Fatty-acid oxidation studies
• Energy metabolism research
• Nuclear receptor research
• Small-molecule pharmacology

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Handling & Storage

• Store the compound according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the material tightly sealed when not in use.
• A commercial reference specification lists storage at 2–8°C; follow the product-specific CoA for definitive storage requirements.
• Minimize unnecessary temperature fluctuations.
• Handle using appropriate laboratory procedures and protective equipment.
• Consult the applicable Safety Data Sheet (SDS) before handling.

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Product Features

✓ Research Grade Compound

✓ ≥98% HPLC Purity

✓ Defined Small-Molecule Structure

✓ Synthetic Pan-ERR Agonist

✓ ERRα / ERRβ / ERRγ Research Tool

✓ Powder Form

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

SLU-PP-332 is an experimental research compound and has not been established as an approved therapeutic treatment. Research findings involving exercise capacity, metabolism, mitochondrial function, or body composition should not be interpreted as evidence of established clinical efficacy or safety in humans.

Studies reporting metabolic and exercise-related effects of SLU-PP-332 have primarily involved cellular and animal research models.

The exact purity, identity, analytical profile, and storage requirements should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is SLU-PP-332?

SLU-PP-332 is a synthetic small-molecule pan-estrogen-related receptor (ERR) agonist used as a research tool for investigating ERR signaling and metabolic biology.

Is SLU-PP-332 a peptide?

No. SLU-PP-332 is a small-molecule compound, not a peptide. Therefore, it does not have an amino-acid sequence.

What is the molecular formula of SLU-PP-332?

The molecular formula is C₁₈H₁₄N₂O₂.

What is the molecular weight of SLU-PP-332?

The molecular weight is approximately 290.32 g/mol.

What is the CAS number?

The CAS number for SLU-PP-332 is 303760-60-3.

What receptors does SLU-PP-332 target?

SLU-PP-332 has been characterized as a pan agonist of ERRα, ERRβ, and ERRγ, with particularly strong activity toward ERRα.

What is SLU-PP-332 researched for?

It is investigated in research involving ERR signaling, mitochondrial function, cellular respiration, skeletal-muscle biology, metabolic signaling, fatty-acid oxidation, and exercise-responsive pathways.

Is SLU-PP-332 an exercise mimetic?

It has been described in scientific literature as an exercise-mimetic research compound because it activates ERR-dependent molecular programs associated with exercise. This characterization comes from experimental research and should not be interpreted as evidence that it reproduces exercise benefits in humans.

What is the purity of SLU-PP-332?

A commercial research specification lists ≥98% purity by HPLC. Batch-specific purity should be confirmed using the applicable CoA.

Is SLU-PP-332 intended for human use?

No. This research-grade compound is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.