Technical Specifications

Specification	Details
Product Name	Thymosin Alpha-1
Common Name	Thymalfasin
Chemical Name	Acetylated Thymosin Alpha-1
Molecular Formula	C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight	~3108.28 g/mol
Sequence	Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Asn
Sequence Code	Ac-SDAAVDTSSEITTKDLKEKKEVVEEN
Sequence Length	28 amino acids
Purity	≥98%
Form	Lyophilized Peptide
Classification	Synthetic Thymic Peptide
Intended Use	Laboratory Research Only

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Product Overview

Thymosin Alpha-1 (Tα1), also known as thymalfasin, is a synthetic 28-amino-acid peptide derived from prothymosin alpha, a naturally occurring protein associated with thymic and immune-cell biology.

Tα1 has been extensively investigated in laboratory and clinical research involving immune signaling, innate immune responses, T-cell biology, dendritic-cell activity, and host-response pathways.

Its defined peptide sequence and biological activity make it a useful research model for studying interactions between peptide signaling and immune-system function.

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Mechanism of Action

Research has investigated Thymosin Alpha-1 in relation to several biological mechanisms:

Toll-Like Receptor Signaling

Experimental studies have examined Tα1 in relation to Toll-like receptor (TLR) pathways involved in innate immune recognition and cellular signaling.

Dendritic-Cell Research

Research has investigated Tα1 in experimental systems involving dendritic-cell maturation and antigen-presenting cell activity.

T-Cell Signaling

Experimental studies have explored interactions between Tα1 and pathways associated with T-cell activation and immune-cell communication.

Innate Immune Response

Tα1 has been investigated in relation to innate immune signaling and cellular responses to microbial and inflammatory stimuli.

Cytokine Signaling

Laboratory research has examined Tα1 in relation to cytokine production and immune-regulatory pathways.

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Research Applications

Thymosin Alpha-1 may be investigated in laboratory settings involving:

• Immunology research
• Innate immune signaling
• T-cell biology
• Dendritic-cell research
• Toll-like receptor studies
• Cytokine signaling
• Host-response research
• Immune-cell communication
• Peptide structure-function studies
• Cellular signaling research
• Thymic peptide research

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Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Store at approximately −20°C when consistent with supplier specifications.
• Follow the applicable batch Certificate of Analysis for exact storage requirements.
• Minimize unnecessary temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Protect the material from prolonged exposure to moisture and light.

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Product Features

✓ Research Grade Quality

✓ ≥98% Purity

✓ 28-Amino-Acid Peptide

✓ Acetylated Peptide Structure

✓ Ac-SDAAVDTSSEITTKDLKEKKEVVEEN Sequence

✓ Lyophilized for Stability

✓ Synthetic Thymic Peptide

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

Thymosin Alpha-1 is an experimental research peptide when supplied for laboratory research. Research findings should not be interpreted as established evidence of clinical efficacy or safety for unapproved applications.

The exact purity, molecular characterization, acetylation status, salt form, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is Thymosin Alpha-1?

Thymosin Alpha-1 is a synthetic 28-amino-acid peptide derived from prothymosin alpha and extensively studied in immunology and cellular signaling research.

What is another name for Thymosin Alpha-1?

Thymosin Alpha-1 is also known as Tα1 or thymalfasin.

What is the sequence of Thymosin Alpha-1?

The acetylated sequence is:

Ac-SDAAVDTSSEITTKDLKEKKEVVEEN

How many amino acids does Thymosin Alpha-1 contain?

Thymosin Alpha-1 contains 28 amino-acid residues.

What is Thymosin Alpha-1 researched for?

Tα1 has been investigated in research involving innate immune signaling, T-cell biology, dendritic-cell activity, Toll-like receptor pathways, cytokine signaling, and host-response mechanisms.

Is Thymosin Alpha-1 a peptide?

Yes. It is a synthetic 28-amino-acid peptide.

What form does Thymosin Alpha-1 come in?

Research-grade Thymosin Alpha-1 is commonly supplied as a lyophilized (freeze-dried) peptide.

What is the purity of Thymosin Alpha-1?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Is Thymosin Alpha-1 intended for human use?

No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should Thymosin Alpha-1 be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.