Technical Specifications

Specification	Details
Product Name	SS-31
Chemical Name	Elamipretide
Synonyms	SS-31, MTP-131, Bendavia, Szeto-Schiller Peptide
Strength	10 mg
Molecular Formula	C₃₂H₄₉N₉O₅
Molecular Weight	~639.79 g/mol
CAS Number	736992-21-5
Sequence	D-Arg-Dmt-Lys-Phe-NH₂
Sequence Length	4 amino acids
Purity	≥98%
Form	Lyophilized Peptide
Classification	Mitochondria-Targeted Tetrapeptide
Intended Use	Laboratory Research Only

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Product Overview

SS-31, also known as elamipretide, MTP-131, or the Szeto-Schiller peptide, is a synthetic mitochondria-targeted tetrapeptide composed of D-Arg-Dmt-Lys-Phe-NH₂. The FDA’s Substance Registration System identifies elamipretide as having the molecular formula C₃₂H₄₉N₉O₅ and molecular weight of approximately 639.79 g/mol.

SS-31 has been extensively investigated in experimental research involving mitochondrial biology, cardiolipin interactions, oxidative-stress pathways, cellular energy metabolism, and mitochondrial function.

Unlike conventional peptides that primarily act through cell-surface receptors, SS-31 has been studied for its ability to interact with mitochondrial membranes and cardiolipin, making it a useful research tool for investigating mitochondrial structure and function.

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Mechanism of Action

Research has investigated SS-31 in relation to several biological mechanisms:

Mitochondrial Targeting

SS-31 is designed as a mitochondria-targeted peptide and has been investigated for its ability to accumulate within mitochondria and interact with mitochondrial membrane components.

Cardiolipin Research

Experimental research has examined the interaction between SS-31 and cardiolipin, a phospholipid that plays an important structural role within the inner mitochondrial membrane.

Oxidative Stress Research

SS-31 has been investigated in experimental models examining mitochondrial oxidative stress and reactive oxygen species-related cellular processes.

Mitochondrial Bioenergetics

Research has explored SS-31 in relation to mitochondrial respiration, electron-transport processes, and cellular energy metabolism.

Mitochondrial Membrane Research

Experimental studies have investigated how SS-31 interactions with mitochondrial membranes may influence membrane organization and mitochondrial function.

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Research Applications

SS-31 may be investigated in laboratory settings involving:

• Mitochondrial biology research
• Cardiolipin interaction studies
• Oxidative-stress research
• Mitochondrial membrane studies
• Cellular bioenergetics research
• Electron-transport-chain studies
• Cellular energy metabolism
• Mitochondrial signaling research
• Peptide-membrane interaction studies
• Experimental cellular biology

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Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Store at approximately −20°C when consistent with supplier specifications.
• Follow the applicable batch Certificate of Analysis for exact storage requirements.
• Minimize unnecessary temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Protect the material from prolonged exposure to moisture and light.

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Product Features

✓ Research Grade Quality

✓ 10mg Lyophilized Peptide

✓ ≥98% Purity

✓ Synthetic Tetrapeptide

✓ Mitochondria-Targeted Research Peptide

✓ D-Arg-Dmt-Lys-Phe-NH₂ Sequence

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

SS-31/elamipretide is an experimental research compound. Findings from laboratory and clinical research should not be interpreted as evidence of established safety or efficacy for uses outside approved regulatory indications.

The exact purity, molecular characterization, salt form, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is SS-31?

SS-31 is a synthetic mitochondria-targeted tetrapeptide also known as elamipretide, MTP-131, and Bendavia.

What is the sequence of SS-31?

The commonly reported sequence is D-Arg-Dmt-Lys-Phe-NH₂, where Dmt refers to 2′,6′-dimethyl-L-tyrosine.

How many amino acids does SS-31 contain?

SS-31 is a tetrapeptide, meaning it contains four amino-acid residues.

What is the molecular weight of SS-31?

The molecular weight of the active elamipretide molecule is approximately 639.79 g/mol.

What is SS-31 researched for?

SS-31 has been investigated in research involving mitochondrial biology, cardiolipin interactions, oxidative stress, mitochondrial bioenergetics, membrane biology, and cellular energy metabolism.

What is cardiolipin?

Cardiolipin is a specialized phospholipid found predominantly in the inner mitochondrial membrane. It plays an important role in mitochondrial membrane structure and respiratory-chain organization.

What form does SS-31 10mg come in?

SS-31 10mg is supplied as a lyophilized (freeze-dried) synthetic peptide intended for laboratory research.

What is the purity of SS-31?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Is SS-31 intended for human use?

No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should SS-31 be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.