Technical Specifications

Specification	Details
Product Name	PT-141 Nasal Spray
Active Compound	Bremelanotide (PT-141)
Chemical Classification	Synthetic Cyclic Peptide
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	~1025.2 g/mol
Sequence	Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
Sequence Code	XDHFRWK
Sequence Length	7 amino-acid residues
Purity	≥98%
Form	Nasal Spray Solution
Classification	Melanocortin Receptor Research Peptide
Intended Use	Laboratory Research Only

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Product Overview

PT-141, also known as bremelanotide, is a synthetic cyclic heptapeptide originally investigated as a melanocortin receptor agonist.

Bremelanotide interacts with melanocortin receptors, particularly MC3R and MC4R, making it a useful research compound for investigating melanocortin signaling, neuroendocrine pathways, receptor pharmacology, and peptide-receptor interactions.

PT-141 nasal spray provides a pre-formulated research delivery format for laboratory investigations involving intranasal peptide delivery, melanocortin receptor signaling, neuropeptide activity, and structure-activity relationships.

Bremelanotide is also the active ingredient in an FDA-approved prescription product for a specific medical indication; this research formulation should not be represented as or substituted for that approved product.

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Mechanism of Action

Research has investigated PT-141 in relation to several biological pathways:

Melanocortin Receptor Signaling

Bremelanotide acts as a melanocortin receptor agonist, providing a research model for investigating MC3R and MC4R signaling.

Neuroendocrine Signaling

PT-141 has been studied in experimental models involving interactions between melanocortin pathways and neuroendocrine signaling.

Central Nervous System Research

Research has investigated melanocortin receptor activity within neural pathways associated with behavioral and physiological signaling.

Peptide-Receptor Interactions

The cyclic peptide structure provides a useful model for studying receptor binding, molecular interactions, and structure-activity relationships.

Intranasal Delivery Research

The nasal-spray format may be used in laboratory research investigating the formulation and delivery characteristics of peptide compounds through the nasal route.

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Research Applications

PT-141 may be investigated in laboratory settings involving:

• Melanocortin receptor research
• MC3R and MC4R signaling
• Neuroendocrine pathway research
• Neuropeptide signaling
• Peptide-receptor interaction studies
• Central nervous system research
• Intranasal peptide delivery research
• Peptide stability studies
• Structure-activity relationship research
• Synthetic peptide pharmacology

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Handling & Storage

• Store the nasal spray according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the container tightly closed when not in use.
• Avoid exposure to extreme temperatures.
• Follow the applicable batch Certificate of Analysis for exact storage requirements.
• Do not use the product if the container or spray mechanism is damaged or compromised.
• Formulation-specific storage requirements may vary depending on concentration, excipients, preservatives, and packaging.

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Product Features

✓ Research Grade Quality

✓ ≥98% Peptide Purity

✓ Synthetic Cyclic Heptapeptide

✓ Bremelanotide (PT-141)

✓ Melanocortin Receptor Research Compound

✓ Convenient Nasal Spray Format

✓ Pre-Formulated Research Solution

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, consumption, diagnosis, treatment, cure, or prevention of any disease.

PT-141 (bremelanotide) is an active pharmaceutical compound with an FDA-approved prescription formulation. This research-grade nasal spray is not the FDA-approved Vyleesi formulation and should not be represented as an approved pharmaceutical product or as a substitute for it.

The exact concentration, formulation, excipients, preservative system, fill volume, peptide purity, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA) and manufacturer documentation.

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is PT-141?

PT-141, also known as bremelanotide, is a synthetic cyclic peptide that acts on melanocortin receptors and has been investigated extensively in melanocortin and neuroendocrine research.

What is the sequence of PT-141?

The molecular structure is commonly represented as:

Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH

It is a cyclic heptapeptide containing modified amino-acid residues.

How many amino acids does PT-141 contain?

Bremelanotide contains 7 amino-acid residues.

What is PT-141 researched for?

PT-141 may be investigated in research involving melanocortin receptors, neuroendocrine signaling, peptide-receptor interactions, central nervous system pathways, and intranasal peptide delivery.

What form does PT-141 Nasal Spray come in?

This product is supplied as a pre-formulated nasal spray solution rather than a lyophilized powder.

What is the molecular weight of PT-141?

Bremelanotide has a reported molecular weight of approximately 1025.2 g/mol for the free-base molecular form.

What is the purity of PT-141?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Does PT-141 Nasal Spray require reconstitution?

No. A pre-formulated nasal spray is supplied as a ready-to-handle research formulation. Researchers should follow the manufacturer’s documentation for handling and storage.

Is PT-141 Nasal Spray intended for human use?

No. This research formulation is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should PT-141 Nasal Spray be stored?

Store according to the manufacturer’s formulation-specific instructions and protect it from excessive heat, direct sunlight, moisture, and extreme temperatures. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.