Technical Specifications

Specification	Details
Product Name	TB-500
Chemical Name	N-Acetylated Thymosin Beta-4 Fragment
Strength	5 mg
Parent Peptide	Thymosin Beta-4
Sequence	Ac-Lys-Lys-Thr-Glu-Thr-Gln
Sequence Code	Ac-LKKTETQ
Sequence Length	7 amino acids
Purity	≥98%
Form	Lyophilized Peptide
Classification	Synthetic Thymosin Beta-4 Fragment
Intended Use	Laboratory Research Only

---

Product Overview

TB-500 is a synthetic peptide associated with the 17–23 region of thymosin β4, a naturally occurring 43-amino-acid peptide. The FDA describes TB-500 as an N-acetylated heptapeptide containing the amino-acid sequence LKKTETQ corresponding to residues 17 through 23 of thymosin β4.

TB-500 has been investigated in experimental research involving cell migration, cytoskeletal dynamics, tissue biology, angiogenesis, and cellular repair mechanisms.

Because terminology surrounding TB-500 varies between suppliers, researchers should verify the exact molecular identity, modification, salt form, and analytical specifications against the product’s Certificate of Analysis.

---

Mechanism of Action

Research has investigated TB-500 and related thymosin β4 sequences in relation to several biological mechanisms:

Actin & Cytoskeletal Research

The thymosin β4 family is associated with actin regulation, making TB-500-related sequences useful for investigating cytoskeletal organization and cellular movement.

Cell Migration Research

Experimental studies have examined thymosin β4-related signaling in cellular migration and movement, particularly in tissue and wound biology models.

Angiogenesis Research

Thymosin β4-related research has investigated signaling pathways associated with vascular development and endothelial-cell activity.

Tissue Biology Research

TB-500 and related thymosin β4 research compounds have been investigated in experimental models involving cellular repair and tissue-remodeling processes.

Cellular Signaling

Research has examined thymosin β4-related peptides in relation to signaling pathways involved in cell survival, migration, differentiation, and tissue responses.

---

Research Applications

TB-500 may be investigated in laboratory settings involving:

• Thymosin β4 research
• Actin-binding studies
• Cytoskeletal biology
• Cell migration research
• Cellular repair studies
• Angiogenesis research
• Endothelial-cell research
• Tissue-remodeling studies
• Cell signaling research
• Synthetic peptide research

---

Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Store at approximately −20°C when consistent with supplier specifications.
• Follow the applicable batch Certificate of Analysis for exact storage requirements.
• Minimize unnecessary temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Protect the material from prolonged exposure to moisture and light.

---

Product Features

✓ Research Grade Quality

✓ 5mg Lyophilized Peptide

✓ ≥98% Purity

✓ Synthetic Thymosin Beta-4 Fragment

✓ Ac-LKKTETQ Sequence

✓ 7-Amino-Acid Peptide

✓ Carefully Packaged

✓ Laboratory Research Use Only

---

Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

TB-500 is an experimental research compound. Findings from laboratory and preclinical research should not be interpreted as established evidence of clinical efficacy or safety for human use.

The exact identity, purity, molecular characterization, acetylation status, salt form, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

---

Frequently Asked Questions

What is TB-500?

TB-500 is a synthetic peptide associated with the 17–23 region of thymosin β4. The FDA describes it as an N-acetylated heptapeptide containing the sequence LKKTETQ.

What is the sequence of TB-500?

The FDA-described sequence is:

Ac-Lys-Lys-Thr-Glu-Thr-Gln

or:

Ac-LKKTETQ.

How many amino acids does TB-500 contain?

The FDA-described TB-500 structure contains seven amino-acid residues with N-terminal acetylation.

What is TB-500 derived from?

TB-500 corresponds to residues 17–23 of thymosin β4, a naturally occurring 43-amino-acid peptide.

What is TB-500 researched for?

TB-500 and related thymosin β4 research have been investigated in areas including actin dynamics, cell migration, angiogenesis, cytoskeletal biology, cellular repair, and tissue biology.

Is TB-500 the same as full-length thymosin β4?

No. Full-length thymosin β4 is a 43-amino-acid peptide, whereas the FDA-described TB-500 is an N-acetylated fragment corresponding to residues 17–23.

What form does TB-500 5mg come in?

TB-500 5mg is supplied as a lyophilized (freeze-dried) synthetic peptide intended for laboratory research.

What is the purity of TB-500?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Is TB-500 intended for human use?

No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should TB-500 be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.