Technical Specifications
| Specification | Details |
|---|---|
| Product Name | SS-31 |
| Chemical Name | Elamipretide |
| Synonyms | SS-31, MTP-131, Bendavia, Szeto-Schiller Peptide |
| Strength | 50 mg |
| Molecular Formula | C₃₂H₄₉N₉O₅ |
| Molecular Weight | ~639.79 g/mol |
| CAS Number | 736992-21-5 |
| Sequence | D-Arg-Dmt-Lys-Phe-NH₂ |
| Sequence Length | 4 amino acids |
| Purity | ≥98% |
| Form | Lyophilized Peptide |
| Classification | Mitochondria-Targeted Tetrapeptide |
| Intended Use | Laboratory Research Only |
Product Overview
SS-31, also known as elamipretide, MTP-131, or the Szeto-Schiller peptide, is a synthetic mitochondria-targeted tetrapeptide composed of D-Arg-Dmt-Lys-Phe-NH₂. The FDA identifies elamipretide with a molecular formula of C₃₂H₄₉N₉O₅ and molecular weight of approximately 639.79 g/mol.
SS-31 has been investigated extensively in experimental research involving mitochondrial biology, cardiolipin interactions, oxidative-stress pathways, mitochondrial membrane function, and cellular bioenergetics.
The peptide is designed to interact with mitochondrial membranes and has been particularly studied in relation to cardiolipin, a specialized phospholipid located within the inner mitochondrial membrane.
Mechanism of Action
Research has investigated SS-31 in relation to several biological mechanisms:
Mitochondrial Targeting
SS-31 is a mitochondria-targeted peptide investigated for its ability to associate with mitochondrial membranes and study mitochondrial structure and function.
Cardiolipin Research
Experimental research has examined SS-31 interactions with cardiolipin, an important phospholipid involved in the organization and function of the inner mitochondrial membrane.
Oxidative Stress Research
SS-31 has been investigated in experimental models examining mitochondrial oxidative stress and reactive oxygen species-related cellular processes.
Mitochondrial Bioenergetics
Research has explored SS-31 in relation to mitochondrial respiration, electron-transport processes, and cellular energy metabolism.
Mitochondrial Membrane Research
Experimental studies have examined how SS-31 interactions with mitochondrial membrane components may influence membrane organization and mitochondrial function.
Research Applications
SS-31 may be investigated in laboratory settings involving:
- Mitochondrial biology research
- Cardiolipin interaction studies
- Oxidative-stress research
- Mitochondrial membrane studies
- Cellular bioenergetics research
- Electron-transport-chain studies
- Cellular energy metabolism
- Mitochondrial signaling research
- Peptide-membrane interaction studies
- Experimental cellular biology
Handling & Storage
- Store the lyophilized peptide according to the manufacturer’s recommended conditions.
- Protect from excessive heat, moisture, and direct sunlight.
- Keep the product sealed in its original packaging until required for laboratory research.
- Store at approximately −20°C when consistent with supplier specifications.
- Follow the applicable batch Certificate of Analysis for exact storage requirements.
- Minimize unnecessary temperature fluctuations.
- Avoid repeated freeze-thaw cycles where applicable.
- Protect the material from prolonged exposure to moisture and light.
Product Features
✓ Research Grade Quality
✓ 50mg Lyophilized Peptide
✓ ≥98% Purity
✓ Synthetic Tetrapeptide
✓ Mitochondria-Targeted Research Peptide
✓ D-Arg-Dmt-Lys-Phe-NH₂ Sequence
✓ Carefully Packaged
✓ Laboratory Research Use Only
Important Notice
This product is intended exclusively for laboratory research purposes.
It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.
SS-31/elamipretide is an experimental research compound when supplied in this research context. Findings from laboratory and clinical research should not be interpreted as evidence supporting unapproved uses.
The exact purity, molecular characterization, salt form, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).
By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.
Frequently Asked Questions
What is SS-31?
SS-31 is a synthetic mitochondria-targeted tetrapeptide also known as elamipretide, MTP-131, Bendavia, and Szeto-Schiller peptide.
What is the sequence of SS-31?
The commonly reported sequence is D-Arg-Dmt-Lys-Phe-NH₂, where Dmt refers to 2′,6′-dimethyl-L-tyrosine.
How many amino acids does SS-31 contain?
SS-31 is a tetrapeptide, meaning it contains four amino-acid residues.
What is the molecular weight of SS-31?
The molecular weight of the elamipretide active molecule is approximately 639.79 g/mol.
What is SS-31 researched for?
SS-31 has been investigated in research involving mitochondrial biology, cardiolipin interactions, oxidative stress, mitochondrial bioenergetics, membrane biology, and cellular energy metabolism.
What is cardiolipin?
Cardiolipin is a specialized phospholipid found predominantly in the inner mitochondrial membrane. It contributes to mitochondrial membrane structure and respiratory-chain organization.
What form does SS-31 50mg come in?
SS-31 50mg is supplied as a lyophilized (freeze-dried) synthetic peptide intended for laboratory research.
What is the purity of SS-31?
This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.
Is SS-31 intended for human use?
No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.
How should SS-31 be stored?
The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.







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