Technical Specifications

Specification	Details
Product Name	PT-141
Common Name	Bremelanotide
Chemical Name	Bremelanotide
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	~1025.18 g/mol
CAS Number	189691-06-3
Sequence	Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Sequence Code	Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Sequence Length	7 amino-acid residues
Purity	≥98%
Form	Lyophilized Peptide
Classification	Synthetic Melanocortin Receptor Agonist
Intended Use	Laboratory Research Only

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Product Overview

PT-141, also known as bremelanotide, is a synthetic cyclic peptide derived from the melanocortin peptide family.

It has been investigated as a melanocortin receptor agonist, with research focusing primarily on melanocortin receptor signaling and related physiological pathways.

PT-141 provides researchers with a defined synthetic peptide model for investigating melanocortin receptor activity, cellular signaling, and neuroendocrine pathways.

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Mechanism of Action

Research has investigated PT-141 in relation to several biological mechanisms:

Melanocortin Receptor Activity

PT-141 interacts with melanocortin receptor pathways, with research particularly focusing on MC3R and MC4R signaling.

MC4R Signaling

Experimental studies have investigated the relationship between PT-141 and MC4R-mediated signaling pathways involved in neuroendocrine and behavioral research.

Neuroendocrine Research

PT-141 has been investigated in experimental models examining interactions between melanocortin signaling and central nervous system pathways.

Cellular Signaling

Research involving PT-141 provides a model for studying receptor-mediated signaling associated with melanocortin peptides.

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Research Applications

PT-141 may be investigated in laboratory settings involving:

• Melanocortin receptor research
• MC3R and MC4R signaling
• Neuroendocrine research
• Receptor pharmacology
• Central nervous system signaling
• Peptide structure-activity studies
• Cellular signaling research
• Synthetic peptide research
• Molecular pharmacology

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Handling & Storage

• Store the lyophilized peptide according to the manufacturer’s recommended conditions.
• Protect from excessive heat, moisture, and direct sunlight.
• Keep the product sealed in its original packaging until required for laboratory research.
• Store at approximately −20°C when consistent with supplier specifications.
• Follow the applicable batch Certificate of Analysis for exact storage requirements.
• Minimize unnecessary temperature fluctuations.
• Avoid repeated freeze-thaw cycles where applicable.
• Protect the material from prolonged exposure to moisture and light.

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Product Features

✓ Research Grade Quality

✓ ≥98% Purity

✓ Lyophilized Peptide

✓ Synthetic Melanocortin Receptor Agonist

✓ Cyclic Peptide Structure

✓ Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH

✓ Carefully Packaged

✓ Laboratory Research Use Only

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Important Notice

This product is intended exclusively for laboratory research purposes.

It is not intended for human or veterinary use, administration, injection, consumption, diagnosis, treatment, cure, or prevention of any disease.

PT-141/bremelanotide is associated with an FDA-approved prescription medication under specific conditions. This research-grade product should not be represented as an equivalent, substitute, or source of an approved pharmaceutical product.

The research material described here is supplied solely for laboratory investigation. Research findings should not be interpreted as established evidence of safety or efficacy for unapproved uses.

The exact purity, molecular characterization, salt form, and analytical specifications should be verified against the applicable batch Certificate of Analysis (CoA).

By purchasing this product, the purchaser acknowledges that it will be handled only by qualified professionals in appropriate laboratory environments and used in accordance with applicable laws, regulations, and institutional protocols.

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Frequently Asked Questions

What is PT-141?

PT-141, also known as bremelanotide, is a synthetic cyclic peptide that has been investigated for its activity within the melanocortin receptor system.

What is the sequence of PT-141?

PT-141 is a cyclic heptapeptide with the structure:

Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH

How many amino acids does PT-141 contain?

PT-141 contains seven amino-acid residues in its cyclic peptide structure.

What is the molecular weight of PT-141?

The molecular weight of bremelanotide is approximately 1025.18 g/mol.

What is PT-141 researched for?

PT-141 is investigated primarily in research involving melanocortin receptors, MC3R/MC4R signaling, neuroendocrine pathways, receptor pharmacology, and peptide-mediated cellular signaling.

Is PT-141 a peptide?

Yes. PT-141 is a synthetic cyclic peptide belonging to the melanocortin peptide family.

What form does PT-141 come in?

Research-grade PT-141 is commonly supplied as a lyophilized (freeze-dried) peptide.

What is the purity of PT-141?

This product is specified at a minimum purity of ≥98%, subject to the applicable batch Certificate of Analysis.

Is PT-141 intended for human use?

No. This research-grade product is supplied strictly for laboratory research purposes and is not intended for human or veterinary use.

How should PT-141 be stored?

The lyophilized peptide should be protected from heat, moisture, and direct sunlight and stored according to the manufacturer’s recommended conditions. Always refer to the batch-specific Certificate of Analysis for exact storage requirements.